Assessment of global DNA methylation in the first trimester fetal tissues exposed to maternal cigarette smoking.

Svetlana FaTrine Vilsbøll LarsenKatrine BildeTina F DaugaardEmil H ErnstRasmus H OlesenLinn S MamsenErik ErnstAgnete LarsenAnders Lade Nielsen

Published in: Clinical epigenetics (2016)

Acknowledging that only examining subsets of global DNA methylation markers and fetal sample availability represents possible limitations for the analyses, our presented results indicate that the first trimester maternal cigarette smoking is not manifested in immediate aberrations of fetal global DNA methylation.

Keyphrases

dna methylation
gene expression
genome wide
copy number
birth weight
pregnancy outcomes
peripheral blood
weight loss
physical activity
preterm birth