ZRSR2 overexpression is a frequent and early event in castration-resistant prostate cancer development.

Haiqing HeJun HaoXin DongYu WangHui XueSifeng QuStephen Yiu Chuen ChoiXinpei CiYong WangRebecca WuMingchen ShiXiaokun ZhaoColin CollinsDong LinYuzhuo Z Wang

Published in: Prostate cancer and prostatic diseases (2021)

Using our unique HNPC PDX models that develop into CRPC after host castration, we identified ZRSR2 as a potential early driver of CRPC development.

Keyphrases

cell proliferation
transcription factor
risk assessment
human health