Diagnostic Utility of MOG Antibody Testing in Cerebrospinal Fluid.
Vyanka RedenbaughJames P FryerLaura CacciaguerraJohn J ChenTammy M GreenwoodMichael GilliganSmathorn ThakolwiboonMasoud MajedNicholas H ChiaAndrew McKeonJohn R MillsAlfonso Sebastian Lopez-ChiribogaJan-Mendelt TillemaBinxia YangYahya AbdulrahmanKai GuoNisa VorasootCristina Valencia SanchezDeena A TajfirouzMichel ToledanoAnastasia ZekeridouDivyanshu DubeyGrace Y GombolayCésar Caparó-ZamalloaIlya KisterSean J PittockEoin Patrick FlanaganPublished in: Annals of neurology (2024)
CSF MOG-IgG testing has diagnostic utility in patients with a suspicious phenotype but negative serum MOG-IgG, and those with low positive serum MOG-IgG results and diagnostic uncertainty. These findings support a role for CSF MOG-IgG testing in the appropriate clinical setting. ANN NEUROL 2024;96:34-45.