Login / Signup

Multi locus sequence typing of Burkholderia pseudomallei isolates from India unveils molecular diversity and confers regional association in Southeast Asia.

Veeraraghavan BalajiSusmitha PerumallaRajamani PerumalFrancis Yesurajan InbanathanSuresh Kumar Rajamani SekarMiracle Magdelene PaulRani Diana SahniJohn Antony Jude PrakashRamya Iyadurai
Published in: PLoS neglected tropical diseases (2018)
Molecular typing of B. pseudomallei clinical isolates using MLST revealed high genetic diversity and provided a baseline molecular epidemiology of the disease in India with a strong Southeast Asian association of the strains. Future studies should focus on whole genome based Single-Nucleotide-Polymorphism (SNP) which has the advantage of a high discriminatory power, to further understand the novel sequence types reported in this study.
Keyphrases
  • genetic diversity
  • escherichia coli
  • single molecule
  • genome wide
  • gene expression
  • dna methylation
  • high density
  • genome wide association study