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RING1 Inhibition Has a Cell-Specific Antitumoral Role by Promoting Autophagy in Endometrial Cancer Cells.

Aleksandra SzustkaKarolina KozalAnna Krześlak
Published in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology (2024)
The results indicate the importance of the RINGs in the process of autophagy and apoptosis. Further potentially more effective combinations of PRT4165 with autophagy modulators should be sought.
Keyphrases
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress
  • signaling pathway
  • cell cycle arrest
  • single cell
  • small molecule
  • cell therapy
  • stem cells
  • pi k akt
  • mesenchymal stem cells