Role of IL33 in chronic inflammation and microvascular damage as a reflection of organ damage on a cohort of patients with acromegaly.

D CostaC PellicanoV MercuriE D'AscanioG BuglioneG CicolaniU BasileG LeodoriPatrizia GargiuloE Rosato

Published in: Journal of endocrinological investigation (2024)

Serum IL33 is higher in AP compared to HC; conversely a reduction of PBP of hands was present in AP compared to HC, probably due to endothelial dysfunction, strictly dependent on acromegaly and are not influenced by the choice of treatment.

Keyphrases

oxidative stress
transcription factor
growth hormone
combination therapy
replacement therapy