Ferulic Acid Activates SIRT1-Mediated Ferroptosis Signaling Pathway to Improve Cognition Dysfunction in Wilson's Disease.

Xie WangNan ShaoXiao-Yan Zhang Hong Chen Ze ChangDaojun XieJuan Zhang

Published in: Neuropsychiatric disease and treatment (2023)

FA alleviates hippocampal neuronal injury by activating SIRT1-mediated FPT, providing a valuable candidate for traditional Chinese medicine monomer for the clinical therapeutics of WD cognitive impairment.

Keyphrases

signaling pathway
cognitive impairment
oxidative stress
ischemia reperfusion injury
pi k akt
cell death
small molecule
induced apoptosis
molecularly imprinted
cell proliferation
brain injury
subarachnoid hemorrhage
endoplasmic reticulum stress
simultaneous determination
temporal lobe epilepsy