A carbapenem-resistant Acinetobacter baumannii outbreak associated with a polymyxin shortage during the COVID pandemic: an in vitro and biofilm analysis of synergy between meropenem, gentamicin and sulbactam.

Viviane ChaibenCarolina Hikari YamadaJoão Paulo TellesAna Paula de AndradeLavinia Nery Villa Stangler ArendVictoria Stadler Tasca RibeiroLeticia Ramos DantasPaula Hansen SussFelipe Francisco Tuon

Published in: The Journal of antimicrobial chemotherapy (2022)

Our study demonstrates the potential role of antibiotic combinations against planktonic bacteria. In vitro synergism is possible and can be an alternative treatment for patients with CRAB infection during a polymyxin shortage.

Keyphrases

acinetobacter baumannii
multidrug resistant
pseudomonas aeruginosa
gram negative
drug resistant
cystic fibrosis
staphylococcus aureus
candida albicans
risk assessment
climate change
smoking cessation