Time Trends in the Treatment and Survival of 5036 Uveal Melanoma Patients in The Netherlands over a 30-Year Period.

Thaïs M L TongEsther BastiaannetFrank M SpeetjensChristian U BlankGregorius P M LuytenMartine J JagerMarina MarinkovicT H Khanh VuCoen R N RaschCarien L CreutzbergJan-Willem M BeenakkerHenk H HartgrinkJacobus J J BoschEmine KiliçNicole C NausSerdar YavuzyigitogluCaroline M van RijMark C Burgmans Ellen H W Kapiteijn

Published in: Cancers (2023)

In this study of patients with primary UM, there was a shift to the diagnosis of smaller tumors, possibly due to stage migration. There was also an increase in eye-preserving treatments over time. OS and CSS were modestly improved in the second time period; however, the time period was not associated with OS or CSS in multivariate analyses.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
patient reported
smoking cessation
skin cancer