WHO/ISUP grade and pathological T stage of clear cell renal cell carcinoma: value of ZOOMit diffusion kurtosis imaging and chemical exchange saturation transfer imaging.

Shichao LiKangwen HeGuanjie YuanXingwang YongXiaoyan MengCui FengYi ZhangIhab R KamelZhen Li

Published in: European radiology (2022)

• Both diffusion kurtosis imaging (DKI) and chemical exchange saturation transfer (CEST) can be used to predict the WHO/ISUP grade and pathological T stage. • MTRasym (3.5 ppm) combined with MD showed the highest AUC (0.930; 95% CI, 0.858-1.000) in WHO/ISUP grading. • MTRasym at 3.5 ppm showed a positive correlation with mean kurtosis.

Keyphrases

high resolution
diffusion weighted imaging
molecular dynamics
computed tomography
mass spectrometry
magnetic resonance