Caffeic acid regulates glucose homeostasis and inhibits purinergic and cholinergic activities while abating oxidative stress and dyslipidaemia in fructose-streptozotocin-induced diabetic rats.

Veronica F SalauOchuko Lucky ErukainureOmamuyovwi M IjomoneMd Shahidul Islam

Published in: The Journal of pharmacy and pharmacology (2022)

The results suggest caffeic acid as a potent natural product with therapeutic effects against T2D. Further molecular and clinical studies are, however, required to ascertain these findings.

Keyphrases

diabetic rats
oxidative stress
ischemia reperfusion injury
dna damage
induced apoptosis
blood glucose
type diabetes
single molecule
high glucose
signaling pathway
endoplasmic reticulum stress
high fat diet
heat stress
drug induced