Microsomal Prostaglandin E Synthase-1 (mPGES-1) is involved in the metabolic and cardiovascular alterations associated with obesity.

Constanza Ballesteros-MartinezRaquel Rodrigues-DiezLuis M BeltránRosa Moreno-CarrilesErnesto Martínez-MartínezMaría González-AmorJose Martínez-GonzálezCristina RodríguezVictoria CachofeiroMercedes SalaicesAna M Briones

Published in: British journal of pharmacology (2021)

mPGES-1 inhibition might be a novel therapeutic approach for the management of obesity and the associated cardiovascular and metabolic alterations.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
physical activity