Combined detection of SHOX2 and PTGER4 methylation with serum marker CYFRA21-1 for improved diagnosis of malignant pleural mesothelioma.

Nana ZhangYongmeng LiZuyu SunYujie DongLijuan ZhouChen ZhangZichen LiuQiuyi ZhangKun LiFudong XuLi ZhangBin SheXiaosha RenNan-Ying Che

Published in: Journal of clinical pathology (2024)

methylation alongside serum CYFRA21-1 level significantly enhances the diagnosis of MPM. Additionally, CYFRA21-1 can serve as a prognostic indicator for MPM.

Keyphrases

dna methylation
genome wide
real time pcr
label free
sensitive detection