mtor Haploinsufficiency Ameliorates Renal Cysts and Cilia Abnormality in Adult Zebrafish tmem67 Mutants.

Ping ZhuQi QiuPeter C HarrisXiaolei XuXueying Lin

Published in: Journal of the American Society of Nephrology : JASN (2021)

Adult zebrafish tmem67 mutants offer a new vertebrate model for renal cystic diseases, in which cilia morphology can be analyzed at a single-nephron resolution and mTOR inhibition proves to be a candidate therapeutic strategy.

Keyphrases

cell proliferation
wild type
young adults