Impact of cardiovascular health and genetic risk on coronary artery disease in Chinese adults.

Qingmei CuiZhongying LiuJianxin LiFangchao LiuXiaoge NiuChong ShenDongsheng HuKeyong HuangShufeng ChenYingxin ZhaoFanghong LuXiaoqing LiuJie CaoLaiyuan WangHongxia MaLing YuXianping WuYing LiHuan ZhangXingbo MoLiancheng ZhaoZhibin HuHongbing ShenJianfeng HuangXiangfeng Lu Dongfeng Gu

Published in: Heart (British Cardiac Society) (2022)

Favourable CVH profile reduced the CAD relative risk by similar magnitude across PRS categories, while the ARR from favourable CVH was most pronounced in high PRS category. Attaining favourable CVH should be encouraged for all individuals, especially in individuals with high genetic susceptibility.

Keyphrases

coronary artery disease
genome wide
percutaneous coronary intervention
heart failure
cardiovascular events
coronary artery bypass grafting
acute coronary syndrome
left ventricular
atrial fibrillation
transcatheter aortic valve replacement
aortic stenosis