Suspected immune checkpoint inhibitor-induced pulmonary sarcoid reaction in metastatic renal cell carcinoma.
Victoria PurcellBeatrice PretiRicardo FernandesPublished in: Clinical case reports (2022)
We present the case of a 50-year-old male patient with metastatic clear cell renal cell carcinoma (mRCC) who developed a diffuse pulmonary opacification and lymphadenopathy during nivolumab maintenance therapy. This was diagnosed as presumed sarcoid granulomatous inflammatory reaction secondary to immunotherapy, which resolved with holding off therapy and the nivolumab was resumed.
Keyphrases
- metastatic renal cell carcinoma
- pulmonary hypertension
- small cell lung cancer
- squamous cell carcinoma
- oxidative stress
- case report
- pulmonary embolism
- diabetic rats
- rheumatoid arthritis
- low grade
- bone marrow
- mesenchymal stem cells
- drug induced
- interstitial lung disease
- endothelial cells
- smoking cessation
- replacement therapy