Acetaminophen elevates unbound bilirubin levels by the glucose oxidase-peroxidase method.

Shintaro IchimuraHiroki KakitaShimpei AsaiMari MoriSatoru TakeshitaHiroko UedaTomoko KondoWataru OhashiAkihisa OkumuraYasumasa Yamada

Published in: Pediatrics international : official journal of the Japan Pediatric Society (2021)

Our study suggests that administration of acetaminophen is related to higher UB levels by the GOD-POD method. UB values measured by the GOD-POD method should not be used in infants treated with acetaminophen for evaluation of bilirubin neurotoxicity avoidance.

Keyphrases

liver injury
drug induced
metabolic syndrome
weight loss
insulin resistance