Hepatic metabolomics and transcriptomics to study susceptibility to ketosis in response to prepartal nutritional management.

Khuram ShahzadVincenzo LopreiatoYusheng LiangErminio TrevisiJohan S OsorioChuang XuJuan J Loor

Published in: Journal of animal science and biotechnology (2019)

The combined data analyses revealed more extensive alterations of the prepartal liver transcriptome than metabolome in cows overfed energy and developing ketosis postpartum. The causative link between these tissue-level adaptations and onset of clinical ketosis needs to be studied further.

Keyphrases

single cell
rna seq
mass spectrometry
gene expression
electronic health record
high intensity
big data
machine learning
artificial intelligence