Validating cell-free DNA from supernatant for molecular diagnostics on cytology specimens.
Marie E PerroneRebeca AlvarezTawnie T VoMoon-Wook ChungDavid C ChhiengVera A PaulsonBrice G ColbertEric Quentin KonnickEric C HuangPublished in: Cancer cytopathology (2021)
This study confirmed that cfDNA from supernatant is a viable alternative to FFPE cell blocks for molecular biomarker testing using both amplicon-based and capture-based assays with potential for decreasing additional tissue sampling and faster turnaround time.