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Validating cell-free DNA from supernatant for molecular diagnostics on cytology specimens.

Marie E PerroneRebeca AlvarezTawnie T VoMoon-Wook ChungDavid C ChhiengVera A PaulsonBrice G ColbertEric Quentin KonnickEric C Huang
Published in: Cancer cytopathology (2021)
This study confirmed that cfDNA from supernatant is a viable alternative to FFPE cell blocks for molecular biomarker testing using both amplicon-based and capture-based assays with potential for decreasing additional tissue sampling and faster turnaround time.
Keyphrases
  • cell free
  • fine needle aspiration
  • single cell
  • high grade
  • high throughput
  • risk assessment
  • climate change
  • human health
  • mesenchymal stem cells