A nait-associated and previously unreported mutation in the ITGB3 gene with a low frequency in the local population.
Stefan NorrenbrockThomas H MüllerChristiane MayerAndrea DoescherPublished in: Transfusion medicine (Oxford, England) (2021)
This finding of a previously unreported private platelet antigen demonstrates that the identification of the target glycoprotein by MAIPA assay followed by sequencing of the affected gene can be combined with an efficient population screening by real-time PCR with pooling of DNA samples.