Sex-Specific Associations Between Chemotherapy, Chronic Conditions, and Neurocognitive Impairment in Acute Lymphoblastic Leukemia Survivors: A Report From the Childhood Cancer Survivor Study.
Ellen van der PlasWeiyu QiuBrian J NiemanYutaka YasuiQi LiuStephanie B DixonNina S Kadan-LottickChristopher B WeldonBrent R WeilLisa M JacolaTodd M GibsonWendy M LeisenringKevin OeffingerMelissa M HudsonLeslie L RobisonGregory T ArmstrongKevin R KrullPublished in: Journal of the National Cancer Institute (2022)
Neurocognitive impairment is associated with methotrexate, dexamethasone, and chronic health conditions in a sex-specific manner, highlighting the need to investigate physiological mechanisms and monitor impact through survivorship.