A natural BACE1 and GSK3β dual inhibitor Notopterol effectively ameliorates the cognitive deficits in APP/PS1 Alzheimer's mice by attenuating amyloid-β and tau pathology.
Xiaowen JiangHongyuan LuJingda LiWenwu LiuQiong WuZihua XuQinglong QiaoHaotian ZhangHuiyuan GaoQing-Chun ZhaoPublished in: Clinical and translational medicine (2020)