Effects of choline supplementation in mothers with hypothyroidism on the brain-derived neurotrophic factor gene expression changes in pre-pubertal offspring rats.

Siamak SheikhiLeila DerafshpourRazieh AghazadehHojat SayyadiEhsan SabooryMorteza Bagheri

Published in: Molecular biology reports (2022)

It can be concluded that maternal choline supplementation on the first day of gestation until PND 21 improves brain development and cognitive function in pre-pubertal offspring rats regarding control/hypothyroidism groups.

Keyphrases

gene expression
high fat diet
replacement therapy
dna methylation
preterm infants
resting state
birth weight
gestational age
functional connectivity
adipose tissue
type diabetes
metabolic syndrome
skeletal muscle
physical activity
insulin resistance
pregnant women
weight loss