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Infectivity-Enhanced, Conditionally Replicative Adenovirus for COX-2-Expressing Castration-Resistant Prostate Cancer.

Tatyana GavrikovaNaohiko NakamuraJulia DavydovaEmmanuel S AntonarakisMasato Yamamoto
Published in: Viruses (2023)
COX-2 promoter-based, infectivity-enhanced CRAds showed a potent antitumor effect in CRPC/NEPC cells.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • dna methylation
  • gene expression
  • transcription factor
  • cell death
  • endoplasmic reticulum stress
  • oxidative stress
  • signaling pathway
  • anti inflammatory
  • gene therapy
  • pi k akt