Baseline Histological Findings Do Not Predict the Risk of Subsequent Extension in Patients with Limited Ulcerative Colitis.
Yansheng HaoClara YzetRussell B McBrideAryeh StockElisa TiratterraAntonietta D'ErricoAndrea BelluzziEleonora ScaioliPaolo GionchettiGiulia RodaRyan UngaroJean-Frederic ColombelNoam HarpazHuaibin Mabel KoPublished in: Digestive diseases and sciences (2021)
Histological severity of limited UC is not an independent predictor of extension in UC. However, among patients who subsequently extend, severe inflammation at baseline correlates with shorter progression time and severe inflammation when extension occurs. Patients with limited UC but severe histologic inflammation may warrant more frequent endoscopic surveillance.