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Recovery after stroke: the severely impaired are a distinct group.

Anna K BonkhoffThomas M H HopeDanilo BzdokAdrian G GuggisbergRachel L HaweSean P DukelowFrançois CholletDavid J LinChristian GrefkesHoward Bowman
Published in: Journal of neurology, neurosurgery, and psychiatry (2021)
Our work highlights the benefit of simultaneously modelling recovery of severely-to-non-severely impaired patients and demonstrates both shared and distinct recovery patterns. Our findings provide evidence that the severe/non-severe subdivision in recovery modelling is not an artefact of previous confounds. The presented out-of-sample prediction performance may serve as benchmark to evaluate promising biomarkers of stroke recovery.
Keyphrases
  • ejection fraction
  • early onset
  • newly diagnosed
  • patient reported outcomes
  • brain injury
  • blood brain barrier
  • patient reported