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Incident Cancer Risk and Signatures Among Older MUTYH Carriers: Analysis of Population-Based and Genomic Cohorts.

Jonathan M DownieMoeen RiazJing XieMinyi LeeAndrew T ChanPeter GibbsSuzanne G OrchardSuzanne E MahadyRobert P SebraAnne M MurrayFinlay MacraeEric E SchadtRobyn L WoodsJohn J McNeillPaul LacazeManish Gala
Published in: Cancer prevention research (Philadelphia, Pa.) (2022)
Despite absence of loss of heterozygosity in colorectal cancers, elderly male MUTYH carriers appeared to be at increased of colorectal cancer.
Keyphrases
  • cardiovascular disease
  • middle aged
  • copy number
  • genome wide
  • community dwelling
  • gene expression
  • dna methylation
  • young adults
  • childhood cancer