Psathyrins: Antibacterial Diterpenoids from Psathyrella candolleana.
Ya-Pei LiuQuan DaiWen-Xuan WangJuan HeZheng-Hui LiTao FengJi-Kai LiuPublished in: Journal of natural products (2020)
Two skeletally novel tetracyclic diterpenoids, psathyrins A (1) and B (2), have been characterized from cultures of the basidiomycete Psathyrella candolleana. Their structures including absolute configurations were established by means of spectroscopic methods, as well as ECD calculations. They possess a novel 5/5/4/6-fuesd ring system, for which the biosynthetic pathway is proposed. Compounds 1 and 2 inhibited the growth of Staphylococcus aureus and Salmonella enterica.
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