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Low-dimensional nanomaterials for antibacterial applications.

Xi-Le HuYing ShangKai-Cheng YanAdam C SedgwickHui-Qi GanGuo-Rong ChenXiao-Peng HeTony David JamesDaijie Chen
Published in: Journal of materials chemistry. B (2021)
The excessive use of antibiotics has led to a rise in drug-resistant bacteria. These "superbugs" are continuously emerging and becoming increasingly harder to treat. As a result, new and effective treatment protocols that have minimal risks of generating drug-resistant bacteria are urgently required. Advanced nanomaterials are particularly promising due to their drug loading/releasing capabilities combined with their potential photodynamic/photothermal therapeutic properties. In this review, 0-dimensional, 1-dimensional, 2-dimensional, and 3-dimensional nanomaterial-based systems are comprehensively discussed for bacterial-based diagnostic and treatment applications. Since the use of these platforms as antibacterials is relatively new, this review will provide appropriate insight into their construction and applications. As such, we hope this review will inspire researchers to explore antibacterial-based nanomaterials with the aim of developing systems for clinical applications.
Keyphrases
  • drug resistant
  • multidrug resistant
  • acinetobacter baumannii
  • cancer therapy
  • emergency department
  • physical activity
  • drug delivery
  • photodynamic therapy
  • body mass index
  • wound healing
  • drug induced