Neutrophil extracellular trap formation linked to idiopathic pulmonary fibrosis severity and survival.

Scott M MatsonLinh T NgoYui SugawaraVeani FernandoClaudia LugoImaan AzeemAlexis HarrisonAlex AlsupEmily NissenDevin KoestlerMichael P WashburnMichaella J RekowskiPaul J WoltersJoyce S LeeJoshua J SolomonM Kristen Demoruelle

Published in: medRxiv : the preprint server for health sciences (2024)

Neutrophil extracellular trap formation markers were associated with disease severity and worse survival in idiopathic pulmonary fibrosis. These findings suggest neutrophil extracellular trap formation contributes to lung injury and decreased survival and may represent a potential therapeutic target.

Keyphrases

idiopathic pulmonary fibrosis
interstitial lung disease
free survival
risk assessment
climate change
human health