Assessment of mouse VEGF neutralization by ranibizumab and aflibercept.
Yusuke IchiyamaRiko MatsumotoShumpei ObataOsamu SawadaYoshitsugu SaishinMasashi KakinokiTomoko SawadaMasahito OhjiPublished in: PloS one (2022)
Aflibercept but not ranibizumab interacts with mouse VEGF, both in vivo and in vitro. When conducting experiments using anti-VEGF drugs in mice, aflibercept is suitable, but ranibizumab is not.