Synaptotagmin 11 scaffolds MKK7-JNK signaling process to promote stem-like molecular subtype gastric cancer oncogenesis.

Bo-Kyung KimDa-Mi KimHyunkyung ParkSeon-Kyu KimMi-Aie HwangJungwoon LeeMi-Jung KangJae-Eun ByunJoo-Young ImMinho KangKyung Chan ParkYoung Il YeomSeon-Young KimHaiyoung JungDae-Hyuk KweonJae-Ho CheongMisun Won

Published in: Journal of experimental & clinical cancer research : CR (2022)

SYT11 could be a potential therapeutic target as well as a prognostic biomarker in patients with diffuse-type GC, and SYT11-ASO could be used in therapeutic agent development for stem-like molecular subtype diffuse GC.

Keyphrases

low grade
signaling pathway
high grade