Brain Metabolism Related to Mild Cognitive Impairment and Phenoconversion in Patients With Isolated REM Sleep Behavior Disorder.

Eun Jin Yoon Jee-Young Lee Heejung Kim Dallah YooJung Hwan ShinHyunwoo NamBeomseok JeonYu Kyeong Kim

Published in: Neurology (2022)

MCI in iRBD is related to functional and metabolic changes in broad brain areas, particularly the occipital and parietal areas. Moreover, hypometabolism in these brain regions was a predictor of phenoconversion to PD or DLB. Evaluation of cognitive function and neuroimaging characteristics could be useful for risk stratification in patients with iRBD.

Keyphrases

mild cognitive impairment
resting state
cognitive decline
white matter
functional connectivity
physical activity
working memory
sleep quality
brain injury