Low body mass index as a predictor of sputum culture conversion and treatment outcomes among patients receiving treatment for multidrug-resistant tuberculosis in Lesotho.
Lawrence OyewusiChengbo ZengK J SeungStephanie MpindaMikanda KundaCarole D MitnickMakelele KanuMeseret TamiratJoalane MakakaMabatloung MofoloRefiloe MaimeLlang MaamaNinza SenyoBamidele OguntoyinboLwayi MayomboMolly F FrankePublished in: Global health action (2024)
Low BMI was common and associated with the frequency of six-month culture conversion and end-of-treatment outcomes. The association with culture conversion was more pronounced among those not living with HIV. Addressing the myriad factors that drive low BMI in this setting could hasten culture conversion and improve end-of-treatment outcomes. This will require a multipronged approach focused on alleviating food insecurity and enabling prompt diagnosis and treatment of HIV and TB.
Keyphrases
- body mass index
- mycobacterium tuberculosis
- multidrug resistant
- weight gain
- hiv aids
- pulmonary tuberculosis
- hiv infected
- cystic fibrosis
- hiv positive
- physical activity
- hepatitis c virus
- emergency department
- drug resistant
- hiv testing
- gram negative
- klebsiella pneumoniae
- acinetobacter baumannii
- combination therapy
- men who have sex with men
- weight loss