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The association between BRAF mutation class and clinical features in BRAF-mutant Chinese non-small cell lung cancer patients.

Quan LinHaoran ZhangHuaxin DingJun QianAnalyn LizasoJing LinHan Han-ZhangJianxing XiangYuping LiHong Zhu
Published in: Journal of translational medicine (2019)
Our study revealed a 2.8% BRAF mutation rate in Chinese NSCLC patients. Our data also showed a male predominance when all BRAF mutations were considered collectively, and a female predominance for class 1 mutations. Furthermore, BRAF V600E is less likely to have concurrent KRAS mutations comparing to the other two classes.
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