Inhibitory Effect of Lygodium Root on the Cytochrome P450 3A Enzyme in vitro and in vivo.
Yunfang ZhouAilian HuaQuan ZhouPeiwu GengFeifei ChenLianhe YanShuanghu WangCongcong WenPublished in: Drug design, development and therapy (2020)
Acacetin and apigenin could inhibit the activity of the cytochrome P450 3A enzyme in vitro and in vivo, indicating that herbal drug interactions might occur when taking Lygodium root and midazolam synchronously.
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