A novel pathogenetic factor of laryngeal attack in hereditary angioedema? Involvement of protease activated receptor 1.

Henriette FarkasCsilla MájIstván KenesseyAnna SebestyénIldikó KrenczJudit PápayLászló Cervenak

Published in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2022)

Our unique case and novel results correspond to the knowledge about C1-INH and BDKRs observed in plasma; however, it revealed new information about the pathomechanism of HAE attack focusing on the potential involvement of PAR1 in edema formation. This observation, if it is verified by subcutaneous biopsy studies, may designate a new therapeutic target in HAE.

Keyphrases

healthcare
ultrasound guided
angiotensin converting enzyme
health information
fine needle aspiration
human health
risk assessment
binding protein
angiotensin ii
social media