Integrated clinico-molecular profiling of appendiceal adenocarcinoma reveals a unique grade-driven entity distinct from colorectal cancer.

Kanwal P S RaghavJohn P ShenAlexandre A JácomeJennifer L GuerraChristopher P ScallyMelissa W TaggartWai C FooAurelio MatamorosKenna R ShawKeith FournierMichael J OvermanCathy Eng

Published in: British journal of cancer (2020)

Integrated clinico-molecular profiling of AA identified key molecular drivers distinct from CRC. Appendiceal adenocarcinoma has a predominantly grade-driven biology that trumps mutations.

Keyphrases

low grade
squamous cell carcinoma
single cell
single molecule
radiation therapy