Combined Orthoplastic Approach in Fracture-Related Infections of the Distal Tibia.
Andrea SambriMarco PignattiSara TedeschiMaria Elisa Lozano MirallesClaudio GianniniMichele FioreMatteo FilippiniRiccardo CiprianiPierluigi VialeMassimiliano De PaolisPublished in: Microorganisms (2022)
This series reports on the treatment of distal tibia (DT) fracture-related infections (FRI) with a combined orthoplastic approach. Thirteen patients were included. In eight patients with extensive bone involvement and in those with a non-healed fracture, the DT was resected ("staged approach"). In five cases, the DT was preserved ("single-stage approach"). A wide debridement was performed, and the cavity was filled with antibiotic-loaded PerOssal beads. All patients had a soft-tissue defect covered by a free vascularized flap (anterolateral thigh perforator flap in eight cases, latissimus dorsi flap in five). At the final follow-up (mean 25 months, range, 13-37), no infection recurrence was observed. In one patient, the persistence of infection was observed, and the patient underwent a repeated debridement. In two cases, a voluminous hematoma was observed. However, none of these complications impacted the final outcome. The successful treatment of FRI depends on proper debridement and obliteration of dead spaces with a flap. Therefore, when dealing with DT FRI, debridement of infected bone and soft tissues must be as radical as required, with no fear of the need for massive reconstructions.
Keyphrases
- soft tissue
- breast reconstruction
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- case report
- drug delivery
- gene expression
- computed tomography
- minimally invasive
- emergency department
- lymph node
- bone mineral density
- magnetic resonance
- magnetic resonance imaging
- patient reported
- postmenopausal women
- bone loss
- image quality