Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells.
Zhen DaiGuangqi SongAsha BalakrishnanTaihua YangQinggong YuanSelina MöbusAnna-Carina WeissMartin BentlerJi-Min ZhuXuemei JiangXizhong ShenHeike BantelElmar JaeckelAndreas KispertArndt VogelAnna SaborowskiHildegard BüningMichael MannsTobias CantzMichael OttAmar Deep SharmaPublished in: Gut (2019)
Collectively, our findings uncover a protective role of GDF11 during liver fibrosis and suggest a potential application of GDF11 for the treatment of chronic liver disease.