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Comparing balance using the BESTest in Alzheimer, Huntington and Parkinson disease.

Lauren Elizabeth TuethRyan P DuncanBeth E CrownerGammon M Earhart
Published in: Neurodegenerative disease management (2024)
Aim: Individuals with Alzheimer disease (AD), Huntington disease (HD) and Parkinson disease (PD) have impaired balance, and comparing these deficits could improve management of neurological diseases. Methods: Scores on the Balance Evaluation Systems Test (BESTest) were compared across three groups, consisting of individuals with AD, HD and PD in early stages of their respective disease. Results: Individuals with PD had significantly higher scores on the BESTest than individuals with AD (95% CI [4.30, 21.37], p  < 0.01) or HD (95% CI [6.53, 24.18], p  < 0.001). Individuals with AD and HD were not significantly different on the overall BESTest or any of its subsections. Conclusion: AD and HD may have overlapping pathologies resulting in early and similar balance impairments in these groups.
Keyphrases
  • parkinson disease
  • deep brain stimulation
  • blood brain barrier