[Experimental evidence for regenerative treatment of chronic tympanic membrane perforation].
Valerij M SvistushkinVladimir I YusupovA B ShekhterA V ZolotovaZhanna MokoyanM V SvistushkinPublished in: Vestnik otorinolaringologii (2021)
Group A perforations were totally closed 2 weeks after treatment in all animals. In group B, complete closure of perforation was achieved after the third treatment procedure in one case. There were no spontaneous perforation closure in the control group. According to morphological investigation, the restoration of trilaminar structure was observed only in tissue engineering group tympanic membranes.