Associations of Alzheimer's disease risk variants with gene expression, amyloidosis, tauopathy, and neurodegeneration.

Meng-Shan TanYu-Xiang YangWei XuHui-Fu WangLin TanChuan-Tao ZuoQiang DongLan TanJohn SucklingJin-Tai Yunull null

Published in: Alzheimer's research & therapy (2021)

Genetic variants might play functional roles and suggest potential mechanisms in AD pathogenesis, which opens doors to uncover novel targets for AD treatment.

Keyphrases

gene expression
dna methylation
copy number
genome wide
replacement therapy
smoking cessation