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Immune cell phenotyping in low blood volumes for assessment of cardiovascular disease risk, development, and progression: a pilot study.

Yvonne BaumerCristhian A Gutierrez-HuertaAnkit SaxenaPradeep K DagurSteven D LangermanKosuke TamuraJoniqua N CeasarMarcus R AndrewsValerie MitchellBilly S CollinsQuan YuHeather L TeagueMartin P PlayfordChristopher K E BleckNehal N MehtaJ Philip McCoyTiffany M Powell-Wiley
Published in: Journal of translational medicine (2020)
A flow cytometry panel identified differences in granulocytes, monocytes, and lymphocytes between AA and Caucasians which may contribute to increased CVD risk in AA. Moreover, this flow panel identifies immune cell sub-populations and platelet aggregates associated with CVD risk. This flow cytometry panel may serve as an effective method for phenotyping immune cell populations involved in the development and progression of CVD.
Keyphrases
  • flow cytometry
  • cardiovascular disease
  • high throughput
  • type diabetes
  • peripheral blood
  • dendritic cells
  • metabolic syndrome
  • genome wide
  • coronary artery disease
  • dna methylation
  • cardiovascular events
  • genetic diversity