Genetic diversity of circumsporozoite protein in Plasmodium knowlesi isolates from Malaysian Borneo and Peninsular Malaysia.

Eric Tzyy Jiann ChongJoveen Wan Fen NeohTiek Ying LauYvonne Ai-Lian LimHwa Chia ChaiKek Heng ChuaPing-Chin Lee

Published in: Malaria journal (2020)

The csp non-repeat regions are relatively conserved and there is no distinct cluster of P. knowlesi isolates from Malaysian Borneo and Peninsular Malaysia. Distinctive variation data obtained in the C-terminal non-repeat region of csp could be beneficial for the design and development of vaccines to treat P. knowlesi.

Keyphrases

genetic diversity
plasmodium falciparum
electronic health record
transcription factor
big data
protein protein
amino acid
machine learning
binding protein
artificial intelligence