Genome-scale methylation analysis identifies immune profiles and age acceleration associations with bladder cancer outcomes.

Ji-Qing Chen Lucas A Salas John K Wiencke Devin C Koestler Annette M Molinaro Angeline S Andrew John D Seigne Margaret R Karagas Karl T Kelsey Brock C Christensen

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2023)

The findings of this study suggest that bladder cancer outcomes are associated with specific methylation-derived immune cell-type proportions and age acceleration, and these factors could be potential prognostic biomarkers.

Keyphrases

genome wide
dna methylation
type diabetes
risk assessment
human health
climate change