TESC promotes differentiated thyroid cancer development by activating ERK and weakening NIS and radioiodine uptake.

Yawen GuoYefeng CaiFahuan SongLei ZhuYiqun HuYunye LiuWenli MaJingyan GeQian ZengLingling DingLebao LiGuo-Wan ZhengMinghua Ge

Published in: Endocrine (2023)

TESC was highly expressed in DTC tissues and may have promoted metastasis through EMT and induced iodine resistance by downregulating NIS in DTC cells.

Keyphrases

signaling pathway
induced apoptosis
epithelial mesenchymal transition
cell cycle arrest
pi k akt
high glucose
diabetic rats
cell proliferation
gene expression
endoplasmic reticulum stress
cell death
oxidative stress