Higher premorbid serum testosterone predicts COVID-19-related mortality risk in men.

Bu B YeapRoss J MarriottLaurens ManningGirish DwivediGraeme J HankeyFrederick C W WuJeremy K NicholsonKevin Murray

Published in: European journal of endocrinology (2022)

Middle-aged to older men with the highest premorbid serum total testosterone and SHBG concentrations are at greater risk of COVID-19-related mortality. Men could be advised that having relatively high serum testosterone concentrations does not protect against future COVID-19-related mortality. Further investigation of causality and potential underlying mechanisms is warranted.

Keyphrases

middle aged
coronavirus disease
sars cov
replacement therapy
cardiovascular events
risk factors
respiratory syndrome coronavirus
physical activity
cardiovascular disease
current status
drug induced