Earlier treatment initiation is associated with a decreased number of HIV-1 subtype A1 transmissions in Greece.
Evangelia Georgia KostakiIoannis Hodges-MameletzisGkikas MagiorkinisGeorgios AdamisGeorgios XylomenosGeorgios NikolopoulosMarios LazanasMaria ChiniNikos MangafasAthanasios SkoutelisVasileios PapastamopoulosAnastasia AntoniadouAntonios PapadopoulosKonstantinos ProtopapasMina PsichogiouDimitrios BasoulisGeorgios ChrysosDimitra ParaskevaVasileios PaparizosSofia KourkountiHelen SambatakouNikolaos V SipsasMalvina LadaPeriklis PanagopoulosEfstratios MaltezosAngelos HatzakisDimitrios ParaskevisPublished in: Sexually transmitted infections (2020)
Our findings showed that the treatment window is decreasing over time, presumably due to the updated treatment guidelines. Our study also demonstrates that people treated earlier after infection do not transmit at high rates, thus documenting the benefits of early ART initiation in preventing ongoing HIV-1 transmission.