Mechanisms for increased risk of diabetes in chronic liver diseases.

Gianluca Svegliati-Baroni Melania Gaggini Fabrizia Carli Chiara Barbieri Monica Cucco Ramy Youne Chiara Rosso Elisabetta Bugianesi Francesco Rubino

Published in: Liver international : official journal of the International Association for the Study of the Liver (2020)

We observed an increased T2D risk in NAFLD-IGT, CHC-IGT and CHC-NGT mainly because of reduced OGTT-insulin response, while insulin response in NAFLD-NGT compensates the IR thus maintaining normal glycaemia.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
metabolic syndrome
skeletal muscle
weight loss